Indones.J.Chem., 2015,15,56

CONDENSATION OF INDOLE WITH ISATIN
OVER AlCl3/MESOPOROUS ALUMINOSILICATE

Aluminium chloride immobilized on mesoporous aluminosilicate was investigated as catalysts in the
condensation of isatin with indole. AlCl3/mesoporous aluminosilicate (AlCl3/AM) catalysts were prepared by
impregnation of 1, 5, 10 and 15 wt% AlCl3 on the surface of mesoporous aluminosilicate. A maximum conversion of
isatin was achieved using 15% AlCl3/AM catalyst whereas the highest selectivity of 68.97% towards trisindoline was
obtained using pure AM. The activity of the catalysts was depended on their acid site number and surface area. The
number of Brønsted acid and the surface area affected to the conversion of isatin while the total acidity and the
number of Lewis acid influenced the selectivity.