+607-553 4048 fsains@utm.my

Publications

CAID members have published research on cancer and infectious diseases, including studies on drugs, natural products, and animal laboratory models, in various scientific journals and conferences.

RESEARCH ARTICLE

RESEARCH ARTICLE

Optimization of antioxidant activity and antimicrobial effects of Bentong ginger (Zingiber officinale) against Streptococcus mutans

PAPERS

  1. Roslee, N., Ong, W. J., Jemon, K., & Zawawi, W. F. A. W. M. (2025). Anti-cancer activity of curcumin loaded CMC hydrogel combined with near infrared radiation on MCF-7 breast cancer cells. Journal of Materials in Life Sciences, 31–39.
  2. Rosle, N., Yee, W. Y., Salamun, N., Jemon, K., & Zawawi, W. F. A. W. M. (2025). Oil palm empty fruit bunch-derived carboxymethyl cellulose hydrogel as a hydrophilic carrier for curcumin. Materials Letters, Article 139660.
  3. Susilo, R. J. K., Apsari, R., Hayaza, S., Cristian, Y. B., Prasetyo, V. G., Widianti, I., et al. (2025). Green synthesis of selenium nanoparticles from okra (Abelmoschus esculentus) extract with characterization and antioxidant activity. Indonesian Journal of Chemistry, 25(4), 1143–1155.
  4. Chamnanchanunt, S., Jacob, B. A. C., Thanachartwet, V., Desakorn, V., et al. (2025). Spectrum of glucose-6-phosphate dehydrogenase (G6PD) mutations and trends in hemoglobin levels among adult dengue patients in Thailand. PLOS ONE, 20(9), e0332039.
  5. Boonyuen, U., Jacob, B. A. C., Chamchoy, K., Pengsuk, N., Talukam, S., et al. (2025). Improved genetic screening with zygosity detection through multiplex high-resolution melting curve analysis and biochemical characterisation for G6PD deficiency. Tropical Medicine & International Health, 30(5), 437–457.
  6. Yinga, L. J., Ab Latifa, N., & Ab Latifa, N. (2025). Optimization of antioxidant activity and antimicrobial effects of Bentong ginger (Zingiber officinale) against Streptococcus mutans. Optimization, 28, 37–41.
  7. Funga, W. C. K., Ab Latifa, N., & Ab Latifa, N. (2025). Evaluation of antibacterial effect of green tea (Camellia sinensis) against dental pathogen Streptococcus mutans and Streptococcus sobrinus. Evaluation, 8, 10–16.
  8. Zakaria, Z., Hasmoni, S. H., Zawawi, N. A., Ab Latif, N., Ihsan, N., et al. (2025). The implementation of IoT in smart vermicompost workshop: Theory and practical. NALI, 5.
  9. Halim, N. A. A., Zakaria, Z., Ab Latif, N., & Hasmoni, S. H. (2025). Biosorption mechanism of cadmium by acid-treated non-living Rhodopseudomonas strain SBL. Journal of Materials in Life Sciences, 11–18.
  10. To, S. W., Al-Ashwal, R. H. A., Ab Latif, N., & Sani, M. H. (2025). Synthesis and characterisation of biodegradable carboxymethyl cellulose microcarriers from oil palm empty fruit bunch for therapeutic applications. Cellulose, 32(1), 483–503.
  11. Roslee, N., Ong, W. J., Jemon, K., & Zawawi, W. F. A. W. M. (2025). Anti-cancer activity of curcumin loaded CMC hydrogel combined with near infrared radiation on MCF-7 breast cancer cells. Journal of Materials in Life Sciences, 31–39.
  12. Rosle, N., Yee, W. Y., Salamun, N., Jemon, K., & Zawawi, W. F. A. W. M. (2025). Oil palm empty fruit bunch-derived carboxymethyl cellulose hydrogel as a hydrophilic carrier for curcumin. Materials Letters, Article 139660.
  13. Latib, F., Zafendi, M. A. I., & Mohd Lazaldin, M. A. (2025). Therapeutic potential of tocopherol and tocotrienol in glaucoma management. Drug Design, Development and Therapy, 10175–10194.
  14. Hanan, N. S., Sapri, R. A. M., Lazaldin, M. A. M., Zulkapli, A., & Samad, A. F. A. (2025). Ginger extract exhibits systemic antifibrotic potential through miR-21-5p and miR-29b modulation in BALB/c mice. Malaysian Journal of Fundamental and Applied Sciences, 21(5), 2606–2614.
  15. Chen, P., Shi, X., Jiang, J., Cheng, H., Chai, J., Xie, Z., & Sani, M. H. (2025). High-yield astaxanthin production process development and scale-up validation from wild-type Phaffia rhodozyma via parameter optimization and LSTM modeling. Frontiers in Microbiology, 16, 1667396.
  16. Usman, M. H., Kamaroddin, M. F., Sani, M. H., Dabai, A. I., Aliero, A. S., & El-Rayyes, A. (2025). Maximizing harvesting of Chlorella vulgaris via calcium oxide nanoparticle-modified fungal pellet using response surface methodology. Biochemical Engineering Journal, 219, 109700.
  17. Aliero, A. S., Zawawi, N. A., Malek, N. A. N. N., Helmi Sani, M., & Usman, M. H. (2025). Biogenic synthesis of silver nanoparticles using palm oil mill effluent and its antioxidant potential. Waste and Biomass Valorization, 16(7), 3535–3542.
  18. Aliero, A. S., Zawawi, N. A., Malek, N. A. N. N., Sani, M. H., Asraf, M. H., To, S. W., et al. (2025). Biocompatible antibacterial and antibiofilm activities of silver nanoparticles synthesized using palm oil mill effluent. Biomass Conversion and Biorefinery, 15(12), 18297–18310.
  19. Usman, H. M., Kamaroddin, M. F., Sani, M. H., Malek, N. A. N. N., & Omoregie, A. I. (2025). Enhanced microalgae harvesting efficiency using Aspergillus pseudonomiae mycelium modified with calcium oxide nanoparticles. Separation and Purification Technology, 354, 128781.
  20. To, S. W., Al-Ashwal, R. H. A., Ab Latif, N., & Sani, M. H. (2025). Synthesis and characterisation of biodegradable carboxymethyl cellulose microcarriers from oil palm empty fruit bunch for therapeutic applications. Cellulose, 32(1), 483–503.
  21. Wang, Y., Ab Ghani, N. S., Dutta, M., Adachi, S., Katoh, K., Namihira, M., et al. (2025). Integrative epigenomic profiling by high-speed super-resolution imaging and deep learning reveals chromatin state biomarkers.
  22. Deguchi, T., Ab Ghani, N. S., Kurumida, Y., Iida, S., Kobayashi, K., & Saito, Y. (2025). Data-efficient protein mutational effect prediction with weak supervision by molecular simulation and protein language models. Briefings in Bioinformatics, 26(5), bbaf536.
  23. Ghani, N. S. A., Harun, S., Abdullah-Zawawi, M. R., Mohamed-Hussein, Z. A., et al. (2025). A comprehensive step-by-step workflow for biological pathway reconstruction and analysis. Encyclopedia of Bioinformatics and Computational Biology (2nd ed., Vol. 6).
  24. Mazlan, B. M., Juhari, F. H., Malek, N. A. N. N., Lazaldin, M. A. M., & Salim, M. I. M. (2025). Eating disorder biomarkers: Macronutrient regulation of ghrelin and leptin. Journal of Human Centered Technology, 4(1), 68–77.

PAPERS

  1. Nik Malek, N. A. N., Abdul Talib, C., Mohd Nor, N. S., Ibrohim, Matmin, J., Lee, S. L., & Noordin, M. K. (2024). Development of mobile app as an educational tool for understanding nanomedicine. Journal of Human Centered Technology, 3(1), 15–21. https://doi.org/10.11113/humentech.v3n1.63
  2. Yunus, J., Wan Dagang, W. R. Z., Jamaluddin, H., & et al. (2024). Bacterial biofilm growth and perturbation by serine protease from Bacillus Archives of Microbiology, 206, 138. https://doi.org/10.1007/s00203-024-03857-0
  3. Alakbaree, M., Suleiman, M., Abdulsalam, A. H., Al-Hili, A., Omar, M. S. S., Ali, F. H., Ab Latif, N., Hamza, M.A., Amran, S.I. (2024). Understanding acute hemolytic anemia severity through computational analysis of G6PD Chatham variant: Designing a new activator as a potential drug. Malaysian Journal of Fundamental and Applied Sciences, 20(6), 1440–1459. https://doi.org/10.11113/mjfas.v20n6.3876
  4. Yong, S. M., Ab Latif, N., & Ab Latif, N. (2024). Optimization of Piper sarmentosum extract concentration and exposure time to inhibit biofilm formation of dental plaque-causing bacteria. Journal of Materials in Life Sciences (JOMALISC), 3 (2), 20–30. https://doi.org/10.11113/jomalisc.v3.75
  5. Johari, N. A., Hoo, W. Q., Lo, L. T. H., Idris, M. K. H., Amran, S. I., Ab Latif, N., Hasham, R., Jemon, K. (2024). In vitro and in silico evaluation of Acalypha indica ethanolic extract on lipid metabolism-related protein expression on breast cancer cells. Journal of Materials in Life Sciences, (JOMALISC), 3(2), 8–19.https://doi.org/10.11113/jomalisc.v3.74
  6. Johari NA, Sapi’i NA, Jiunn Hieng AL, Ab Latif N, Amran SI, Hasham R, Jemon K. (2024). In vitro and in silico evaluation of Andrographis paniculata ethanolic crude extracts on fatty acid synthase expression on breast cancer cells. BioMedicine, 14(2), https://doi.org/10.37796/2211-8039.1444
  7. Chandran, S., Louis, N. E., Amran, S. I., Ab Latif, N., Hamza, M. A., & Alonazi, M. (2024). Computational analysis of dimer G6PD structure to elucidate pathogenicity of G6PD BioMedicine, 14(1), 47-59. https://doi.org/10.37796/2211-8039.1431
  8. Boonyuen, U., Jacob, B. A. C., Wongwigkan, J., Chamchoy, K., Singha-Art, N., … (2024). Genetic analysis and molecular basis of G6PD deficiency among malaria patients in Thailand: Implications for safe use of 8-aminoquinolines. Malaria Journal, 23(1), https://doi.org/10.1186/s12936-024-04864-8
  9. Louis, N. E., Hamza, M. A., Engku Baharuddin, P. N. S. D., Chandran, S., Latif, N. A., … (2024). Assessing the structural dynamics of the glucose-6-phosphate dehydrogenase dimer interface using molecular dynamics simulation and ligand screening using computer-aided drug discovery. Molecular Simulation, 50(1), 63–74. https://doi.org/10.1080/08927022.2023.2274871
  10. Toh, M. S., Chong, W. C., Susanto, H., Malek, N. A. N. N., & Prabhakaran, P. (2024). Anticancer effects of cisplatin and 6-gingerol co-treatment on MDA-MB-231 breast cancer cells. Journal of Materials in Life Sciences (JOMALISC), 78–87. https://doi.org/10.11113/jomalisc.v3.80
  11. Susanto, H., Sholeh, M., Endharti, A. T., Prabhakaran, P., & Taufiq, A. (2024). Chitosan nanoparticles of Moringa seeds alleviate cell proliferation and metastasis gene expression in breast cancer cell line (MCF-7). Journal of Advanced Pharmaceutical Technology & Research, 15(4), 290–296. https://doi.org/10.4103/JAPTR.JAPTR_32_24
  12. Saim, H., Yassin, S. N. M., Salim, M. I. M., Jemon, K., AlAshwal, R. H., Wahab, A. A., … (2024). Retraction Note: Antitumor effect of infrared whole-body hyperthermia with curcumin in breast cancer. Multimedia Tools and Applications, 83(42), https://doi.org/10.1007/s11042-024-20519-x
  13. Vangetaraman, K., Asiri, A., Sivalingam, S., Shafi, A. A., Jemon, K., & Saidin, S. (2024). Morphology and wettability analyses on electrospun polyvinyl alcohol/elastin nanofibers at varying voltages and composition. Advances in Science and Technology, 143, 41–46. https://doi.org/10.4028/p-arih8r
  14. Latib, F., Zafendi, M. A. I., & Lazaldin, M. A. M. (2024). The use of vitamin E in ocular health: Bridging omics approaches with tocopherol and tocotrienol in the management of glaucoma. Food Chemistry: Molecular Sciences, https://doi.org/10.1016/j.fochms.2024.100224
  15. Aziz, N. A., & Lazaldin, M. A. (2024). Roles of mixed tocopherol and tocotrienol in lowering intraocular pressure in ocular hypertensive rats. Proceedings of Science & Mathematics, 25, 132–139.
  16. Salihu, R., Abd Razak, S. I., Sani, M. H., Wsoo, M. A., Zawawi, N. A., & Shahir, S. (2024). Citrate-modified bacterial cellulose as a potential scaffolding material for bone tissue regeneration. PLOS ONE, 19(12), https://doi.org/10.1371/journal.pone.0312396
  17. Aliero, A. S., Zawawi, N. A., Malek, N. A. N. N., Sani, M. H., Asraf, M. H., To, S. W., … (2024). Biocompatible antibacterial and antibiofilm activities of silver nanoparticles synthesized using palm oil mill effluent. Biomass Conversion and Biorefinery, 1–14. https://doi.org/10.1007/s13399-024-06405-4
  18. Usman, H. M., Kamaroddin, M. F., Sani, M. H., Malek, N. A. N. N., Omoregie, A. I., … (2024). A comparative analysis assessing growth dynamics of locally isolated Chlorella sorokiniana and Chlorella vulgaris for biomass and lipid production with biodiesel potential. Bioresource Technology, 403, https://doi.org/10.1016/j.biortech.2024.130868
  19. Liew, K. J., Shahar, S., Shamsir, M. S., & et al. (2024). Integrating multi-platform assembly to recover MAGs from hot spring biofilms: Insights into microbial diversity, biofilm formation, and carbohydrate degradation. Environmental Microbiome, 19(1), https://doi.org/10.1186/s40793-024-00572-7

 

PAPERS

  1. Abu Bakar, N. F. A. B., Yeo, Z. L., Hussin, F., Madhavan, P., Lim, V., Jemon, K., & Prabhakaran, P. (2023). Synergistic effects of combined cisplatin and Clinacanthus nutans extract on triple negative breast cancer cells. Journal of Taibah University Medical Sciences, 18(6), 1220-1236. https://doi.org/10.1016/j.jtumed.2023.04.003
  2. Alahmmar, M., Prabhakaran, P., Jaganathan, S., & Malek, N. A. N. N. (2023). Fabrication and characterization of polycaprolactone with retinoic acid and cerium oxide for anticancer applications. Biointerface Research in Applied Chemistry, 13.
  3. Abu Bakar, N. F. A. B., Yeo, Z. L., Hussin, F., Madhavan, P., Lim, V., Jemon, K., & Prabhakaran, P. (2023). Synergistic effects of combined cisplatin and Clinacanthus nutans extract on triple negative breast cancer cells. Journal of Taibah University Medical Sciences, 18(6), 1220-1236. https://doi.org/10.1016/j.jtumed.2023.04.003
  4. Malek, N. A. N. N., Shamsuddin, M., Matmin, J., Jemon, K., Samad, A. A., Hassan, M. H. A., & Susanto, H. (2023). Antibacterial wound healing application of bio-inspired green silver nanoparticles: A review. Journal of Materials in Life Sciences (JOMALISC), 2(2), 147–153. https://doi.org/10.11113/jomalisc.v2.43
  5. Khrisna, D. F., Jumat, M. A., Jemon, K., & Saidin, S. (2023). Antibacterial analysis on everolimus grafted biomaterial surfaces using polydopamine intermediate layer for potential use on medical devices. Journal of Human Centered Technology, 2(2), 11–18. https://doi.org/10.11113/humentech.v2n2.52
  6. Hasham, R., Maniarasu, N., Jemon, K., Abd Latif, N., & Bahari, H. (2023). A review on rosmarinic acid rich extract for skin regeneration through rapamycin signaling pathway. Chemical and Natural Resources Engineering Journal (Formally Known As Biological and Natural Resources Engineering Journal), 7(1), 1–9. https://doi.org/10.31436/cnrej.v7i1.85
  7. Alakbaree, M., Abdulqader, A., Abdulsalam, A. H., Hamza, M. A., Amran, S. I., Shamsir, M. S., & Ab Latif, N. (2024). G6PD deficiency: Exploring the relationship with different medical disorders. Journal of Contemporary Medical Sciences, 9(5).
  8. Alakbaree, M., Abdulsalam, A. H., Ahmed, H. H., Ali, F. H., Al-Hili, A., Shamsir Omar, M. S., Alonazi, M., Jamalis, J., Ab Latif, N., Hamza, M. A., & Amran, S. I. (2023). A computational study of structural analysis of Class I human glucose-6-phosphate dehydrogenase (G6PD) variants: Elaborating the correlation to chronic non-spherocytic hemolytic anemia (CNSHA). Computational Biology and Chemistry, 104, 107873. https://doi.org/10.1016/j.compbiolchem.2023.107873
  9. Mohd Ghazi, R., Nik Yusoff, N. R., Abdul Halim, N. S., Wahab, I. R. A., Ab Latif, N., Hasmoni, S. H., & Zakaria, Z. A. (2023). Health effects of herbicides and its current removal strategies. Bioengineered, 14(1). https://doi.org/10.1080/21655979.2023.2259526
  10. Lazaldin, M. A. M., Lambuk, L., Ahmad, S., & Mohamud, R. (2023). Growth factors and their receptors: Multitasking functionality in health and disease. In H. M. Mansour, M. M. Khattab, & A. S. El-khatib (Eds.), Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders (pp. 187-243). Academic Press.
  11. Lazaldin, M. A. M., Iezhitsa, I., Agarwal, R., Agarwal, P., & Ismail, N. M. (2023). Neuroprotective effects of exogenous brain-derived neurotrophic factor on amyloid-beta 1–40-induced retinal degeneration. Neural Regeneration Research, 18(2), 382-388. https://doi.org/10.4103/1673-5374.346546
  12. Chan, S. X. Y., Fitri, N., Mio Asni, N. S., Sayuti, N. H., Azlan, U. K., Qadi, W. S. M., Dawoud, E. A. D., Kamal, N., Sarian, M. N., & Mohd Lazaldin, M. A. (2023). A comprehensive review with future insights on the processing and safety of fermented fish and the associated changes. Foods, 12, 558. https://doi.org/10.3390/foods12030558
  13. Peng, R., Li, D., Wang, J., et al. (2023). Reassortment and genomic analysis of a G9P[8]-E2 rotavirus isolated in China. Virology Journal, 20, 135. https://doi.org/10.1186/s12985-023-02064-5
  14. Wong, C. Y., Tham, J. S., Foo, C. N., Ng, F. L., Shahar, S., Zahary, M. N., Ismail, M. N., Tan, C. S., Hoh, B. P., Kumar, S. V., & Lim, Y. M. (2023). Factors influencing COVID-19 vaccination intention among university students: A cross-sectional study in Malaysia. Biosafety and Health, 5, 37-44.
  15. Peng, R., Li, D., Wang, J., et al. (2023). Isolation and genomic characterization of a reassortant G9P[8]-E2 rotavirus strain in China. Research Square. https://doi.org/10.21203/rs.3.rs-2563661/v1
  16. Usman, M. H., Kamaroddin, M. F., Sani, M. H., & Nik Malek, N. A. N. (2023). Exploring the potential of microalgae-fungi co-cultivation for sustainable bioprocessing in microalgae biorefinery. Malaysian Applied Biology, 52(6), 23-46. https://doi.org/10.55230/mabjournal.v52i6.2783
  17. Radzi, M. R. M., Lim, C. K., Sulaiman, N., & Jemon, K. (2023). Nanoparticles-based chemo-phototherapy synergistic effects for breast cancer treatment: A systematic review. Biointerface Research in Applied Chemistry, 13(3), 232. https://doi.org/10.33263/BRIAC133.232

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